Vibrenta Penset (100IU/ml) 1 Cartridge
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Vibrenta Penset (100IU/ml) 1 Cartridge

Generic: Insulin Glargine (rDNA)

Type: Injection

Pack Size: 3ml

Vibrenta is indicated to enhance glycemic control in adults and children with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus.


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MRP: ৳ 600 5% Off

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✅ Description:

Vibrenta Penset is a long-acting insulin used to manage both type 1 and type 2 diabetes mellitus in adults and children. It provides sustained insulin levels throughout the day to control blood sugar and prevent complications of diabetes. It can be used alone or in combination with fast-acting insulin or other diabetes medications.

Safety Advices


Alcohol
UNSAFE

Consuming alcohol with Vibrenta Penset is unsafe and can lead to adverse effects, particularly by lowering blood sugar levels unpredictably. It's advisable to avoid alcohol consumption while using this medication.


Pregnancy
CONSULT YOUR DOCTOR

Vibrenta Penset may pose risks during pregnancy. Although limited human studies are available, animal studies indicate potential harm to the developing baby. Your doctor will assess the benefits versus risks before prescribing this medication during pregnancy. Consult your doctor if you are pregnant or planning pregnancy.


Breastfeeding
CONSULT YOUR DOCTOR

Vibrenta Penset is considered safe during breastfeeding. Human studies suggest minimal excretion into breast milk, posing little risk to the nursing infant. Nevertheless, consult your doctor before using this medication while breastfeeding.


Driving
UNSAFE

Fluctuations in blood sugar levels (both high and low) can affect your ability to drive. Avoid driving if you experience symptoms of low or high blood sugar levels such as weakness, dizziness, or confusion.


Kidney
CAUTION

Use Vibrenta Penset cautiously if you have kidney disease. Dose adjustments may be necessary. Regular monitoring of blood glucose levels is recommended for appropriate dose adjustments.


LIver
CAUTION

Patients with liver disease should also use Vibrenta Penset with caution. Dose adjustments may be required based on regular monitoring of glucose levels. Consult your doctor for personalized guidance.

Similar Products

✔️ Uses of Vibrenta Penset

Diabetes mellitus

✔️ How does Vibrenta Penset work?

Vibrenta Penset mimics natural insulin action in the body, facilitating glucose uptake into muscle and fat cells while suppressing liver glucose production.

✔️ Side Effects of Vibrenta Penset

Possible side effects include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, itching, and rashes.

✔️ Quick Suggestions:
  • Inject subcutaneously (under the skin) in the upper arm, thigh, or abdomen. Rotate injection sites to prevent skin changes at any one site.
  • Administer once daily at the same time each day for consistent blood sugar control.
  • Regularly monitor blood sugar levels to adjust doses and prevent hypoglycemia.
  • Opened vials/cartridges can be stored at room temperature for up to 4 weeks; unopened vials should be refrigerated (2°C–8°C).
  • Inform your doctor about kidney, liver, or heart issues before starting Vibrenta Penset. Pregnant or breastfeeding women should consult their doctor before use.
✔️ Indication of Vibrenta Penset

Vibrenta is prescribed to improve glycemic control in both adults and children with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus.

✔️ Pharmacology

Insulin Glargine is a sterile solution used for subcutaneous injection. It is a long-acting (up to 24 hours) human insulin analog produced through recombinant DNA technology. Its primary function is to regulate glucose metabolism. It lowers blood glucose by stimulating peripheral glucose uptake, mainly by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin also inhibits lipolysis and proteolysis and enhances protein synthesis.

✔️ Dosage & Administration of Vibrenta Penset

Insulin Glargine should be administered once daily at the same time each day. Dosages are personalized based on clinical response, with regular blood glucose monitoring essential. For Type 1 diabetes, it must be combined with short-acting insulin. It is not suitable for intravenous administration as it may cause severe hypoglycemia.

Starting Therapy:

  • Type 1 Diabetes: Begin with roughly one-third of the total daily insulin requirement, supplementing with short-acting insulin.
  • Type 2 Diabetes (new to insulin): Start with 10 units (or 0.2 units/kg) once daily, adjusting as needed.

Converting from Other Insulin Therapies:

  • From once-daily NPH: Begin with the same dose as the NPH being replaced.
  • From twice-daily NPH: Start with 80% of the total NPH dose being replaced.

Cartridge: Insert into the pen, attach the needle, and mix the insulin by gently turning the pen upside down 8-10 times. Adjust dosage, remove the needle cap, expel air bubbles, and inject.

✔️ Interaction

Various drugs affect glucose metabolism, potentially requiring dose adjustments.

Drugs that may reduce requirements:

  • Oral anti-diabetic drugs, ACE inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, propoxyphene, pentoxifylline, salicylates, sulfonamide antibiotics.

Drugs that may increase requirements:

  • Thiazides, glucocorticoids, thyroid hormones, beta-sympathomimetics, growth hormone, danazol. Beta-blockers, clonidine, lithium, and alcohol may either increase or decrease the effect.
✔️ Contraindications

It is not for use in patients hypersensitive to insulin galline or its ingredients.

✔️ Pregnancy & Lactation

Classified as Pregnancy Category C. Use during pregnancy only if benefits outweigh risks. The excretion in human milk is unknown, so caution is advised for nursing women, with potential dose and dietary adjustments needed.

✔️ Precautions & Warnings

Dose Adjustment and Monitoring: Regular monitoring of blood glucose is necessary. Adjustments should be made under medical supervision.

Administration: Do not dilute or mix with other insulins or solutions. Not for use in insulin pumps or intravenously due to hypoglycemia risk.

Renal or Hepatic Impairment: Dose reductions may be necessary.

✔️ Storage Conditions:

Store between 2°C and 8°C in a refrigerator. Do not freeze and protect from light.

Frequently Asked Questions (FAQ)

Overdosing can cause hypoglycemia. Mild cases can be treated with oral carbohydrates, while severe cases may require glucose or glucagon injections. Adjustments to dosage, diet, or exercise may be needed.

A. Serious side effects are rare but can include severe allergic reactions (rash, hives, trouble breathing, fast heart rate, low blood pressure) and severe hypoglycemia (dizziness, sweating, anxiety, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, seizures, unconsciousness). Taking certain medicines like TZDs may lead to heart failure in some people. Sudden weight gain and swelling of the ankles or feet may also occur. Seek immediate medical attention if you experience any of these symptoms.

A. Store unopened vials and pens in the refrigerator, but do not freeze them. Unopened Insulin Glargine can be kept in the refrigerator until the expiration date on the label. If a refrigerator is unavailable, it can be stored at room temperature, away from direct sunlight and heat. Ensure the solution remains clear and particle-free.

A. Insulin Glargine is injected just below the skin (subcutaneously). Your doctor will guide you on the correct method and suitable injection sites. Rotate injection sites within the chosen area to prevent complications like lipodystrophy. For example, if injecting in the stomach, choose a different spot each time, about 1 cm away from the previous site. Switch to another area (e.g., arms or thighs) after one to two weeks, as advised by your doctor.

A. Dose adjustments may be necessary in various situations such as illness, changes in medication, dietary changes, exercise habits, alcohol consumption, and stress levels. Pregnant and breastfeeding women should consult their doctor for possible dose modifications.

A. Insulin Glargine is a long-acting, man-made insulin similar to human insulin. It has a steady effect on blood sugar levels, lasting for 24 hours, making it suitable for once-daily use. It is used to treat type 1 diabetes in both adults and children and type 2 diabetes in adults.

A. Insulin Glargine is typically prescribed for once-daily use due to its long-acting nature. It can be taken at any time of the day but should be taken at the same time each day for consistency.

A. Injecting more than the prescribed dose may cause hypoglycemia (low blood sugar). Monitor your blood sugar levels closely for the next 24 hours. Mild hypoglycemia can be managed with sugary foods or drinks. Severe hypoglycemia, which may cause seizures or unconsciousness, requires immediate medical attention.

A. Insulin Glargine is injected subcutaneously using a pen device or insulin syringe and needle. Common injection sites include the abdomen, thighs, upper arms, hips, or buttocks. Ensure the solution is colorless and particle-free before use. Follow the prescribed dosage and instructions on administering it, and monitor blood sugar levels regularly.
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Check our pricing section for Vibrenta Penset (100IU/ml) 1 Cartridge price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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